NCT02116426

Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome

The Role of Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 320 (actual)
• Sponsor: Centre Hospitalier Universitaire de Nīmes · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objective of our study is to evaluate the diagnostic value of copeptin testing in association with troponin HS testing during pre-hospital care (ambulance care) in the treatment of patients whose pattern of use is the occurrence chest pain suggestive of ACS but not ST+.

Detailed description

The secondary objectives of this study are to: A. Evaluate the diagnostic value of determination of copeptin testing in pre-hospital care in another diagnosis; B. Assess the prognostic value of copeptin assay on vital prognosis at day 28; C. Evaluate the kinetics of copeptin and troponin HS between initial ambulance care and arrival at the emergency department; D. Evaluate the potential impact of copeptin testing on pre-hospital patient care; E. Assess the economic impact of pre-hospital copeptin testing in terms of hospital stays and optimizing ambulance movements.

Conditions

• Chest Pain

Interventions

Type	Name	Description
BIOLOGICAL	Blood work in the ambulance	Blood sample for copeptin and troponin HS testing is taken during ambulance care.
BIOLOGICAL	Blood work upon arrival in the emergency room	Blood in drawn for copeptin and troponin HS testing upon arrival in the emergency room.
BIOLOGICAL	Blood work at 3 hours post-arrival in the emergency room	Blood is drawn for troponin HS testing 3 hours after the patient's arrival in the emergency room.

Timeline

• Start date: 2015-07-29
• Primary completion: 2017-08-01
• Completion: 2017-08-01
• First posted: 2014-04-16
• Last updated: 2018-01-03

Locations

2 sites across 1 country: France