Clinical Trials Directory

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UnknownNCT02116010

Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients

Phase I/II Clinical Trial Randomized, Multicentric, Open Label, Standard of Care (Silver Sulfadiazine) Controlled Aiming at Assessing Tolerance and Efficacy of Local Bacteriophage Treatment of Wound Infections Due to E. Coli or P. Aeruginosa in Burned Patients Using Pherecydes Pharma Anti-Escherichia Coli and Anti-Pseudomonas Aeruginosa Bacteriophages GMP Produced Cocktails . This Project is a European Research & Development (R&D) Project Funded by the European Commission Under the 7th Framework Programme for Research and Development Involving 7 Clinical Sites in EU.

Status
Unknown
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
Sponsor
Phagenix · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The objective of PHAGOBURN is to assess tolerance and efficacy of local bacteriophage treatment of E. coli or P. aeruginosa wound infections in burned patients.

Detailed description

PHAGOBURN is a Phase I/II clinical trial randomized, multicentric, open label, standard of care (Silver Sulfadiazine) controlled aiming at assessing tolerance and efficacy of local bacteriophage treatment of wound infections due to E. coli or P. aeruginosa in burned patients using Pherecydes Pharma anti-Escherichia coli and anti-Pseudomonas aeruginosa bacteriophage cocktails GMP produced. This project is a European Research \& Development (R\&D) project funded by the European Commission under the 7th Framework Programme for Research and Development. This project is involving 7 clinical sites in EU.

Conditions

Interventions

TypeNameDescription
DRUGE. coli Phages cocktailUse of Pherecydes Pharma Phages cocktail to treat respectively E. coli burn wound infection
DRUGStandard of care : Silver SulfadiazineUse of Standard of care : Silver Sulfadiazine, to treat E. coli or P. aeruginosa infected burn wound
DRUGP. Aeruginosa, Phages cocktailUse of Pherecydes Pharma Phages cocktail to treat P. aeruginosa burn wound infection

Timeline

Start date
2015-07-01
Primary completion
2016-07-01
First posted
2014-04-16
Last updated
2015-07-24

Locations

5 sites across 3 countries: Belgium, France, Switzerland

Source: ClinicalTrials.gov record NCT02116010. Inclusion in this directory is not an endorsement.