Trials / Completed
CompletedNCT02113852
Study of Blood, Tumor and Adjacent Normal Tissue Samples From Chinese Smoking Induced Lung Cancer Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 250 (actual)
- Sponsor
- Guangdong Association of Clinical Trials · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is an epidemiological,multicenter study of genomic and expression profiles of patients with newly diagnosed NSCLC.Two hundred and fifty NSCLC patients who fulfill the criteria are to be recruited by investigational sites.Approximately 100 of them will be from retrospectively collected samples with detailed clinical and 2-year follow-up information after surgeries.The demographics,cancer/adjacent normal tissue and matched blood sample will be collected after the patient had provided informed consent.All tissue samples will be analyzed for somatic mutations by exome deep sequencing,mRNA expression profiling by RNA sequencing and chromosome copy number variation by SNP array at the designated laboratories.
Detailed description
The 2-year follow-up information of all enrolled patients will be collected every 6 months.
Conditions
Timeline
- Start date
- 2013-08-01
- Primary completion
- 2016-05-01
- Completion
- 2016-12-01
- First posted
- 2014-04-15
- Last updated
- 2017-03-01
Source: ClinicalTrials.gov record NCT02113852. Inclusion in this directory is not an endorsement.