Trials / Completed
CompletedNCT02113150
A Comparison of the Effects of Ketamine and Remifentanil on Serum Cystatin-c Levels in CABG Surgery
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 37 (actual)
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
In this prospective, randomized, clinical trial, we have investigated the effects of ketamine-based and remifentanil-based anesthetic protocol on perioperative serum cystatin-c levels, and creatinine and/or cystatin-c based eGFR equations in terms of acute kidney injury in CABG surgery.This study was approved by the Ethics Committee of Hospital and all patients were informed and gave written consent. Patients scheduled for elective CABG with cardiopulmonary bypass. Patients were randomly allocated to anesthesia with remifentanil-propofol-midazolam (RPM) group or ketamine-propofol-midazolam (KPM) group. Blood samples were obtained before induction of anesthesia (baseline), at the end of the operation, and postoperative days 1, 2, and 4.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | remifentanil | renal function |
| DRUG | Ketamine | renal function |
Timeline
- Start date
- 2013-05-01
- Primary completion
- 2013-07-01
- Completion
- 2013-09-01
- First posted
- 2014-04-14
- Last updated
- 2014-04-14
Locations
2 sites across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT02113150. Inclusion in this directory is not an endorsement.