NCT02109315

Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes.

• Status: Withdrawn
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Anna Cruceta · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

To investigate the effect of liraglutide on vascular injury induced hypoglycemia in patients with type 1 diabetes mellitus. The vascular damage is evaluated at investigating the changes of endothelial function

Detailed description

To investigate the effect of antioxidants (Vitamin C) on the vascular damage induced hypoglycemia in patients with type 1 diabetes. The vascular injury was evaluated in the same way as main objective. Checking the existence of a peripheral response to the action of GLP-1 due to oxidative stress.

Conditions

• Type 1 Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	Vitamine C	C Vitamine endovenous 1000 mg/5 ml. Infusion dose: 30 mgr/min
DRUG	Liraglutide 6 mg	Liraglutide endovenous de 0.6 mg. one time a day

Timeline

• Start date: 2014-05-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2014-04-09
• Last updated: 2019-02-15

Locations

1 site across 1 country: Spain