NCT02108730

Towards Individualized Surgery in Non-focal Congenital Hyperinsulinism

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 14 (actual)
• Sponsor: University Medicine Greifswald · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Observational study in patients with non-focal congenital hyperinsulinism showing that restrictive surgery may improve the metabolic situation

Detailed description

In non-focal congenital hyperinsulinism (CHI) the current doctrine warrants subtotal pancreatic resection in all children who do not respond to medication. However, the rate of diabetes after these extensive resections is very high. In this study investigators show that a less aggressive approach may suffice to wean many children from all medication or to get them manageable medically.

Conditions

• Non-focal Congenital Hyperinsulinism

Interventions

Type	Name	Description
PROCEDURE	restrictive pancreatic resection	Restrictive, spleen-preserving resection of the pancreatic tail by laparoscopy

Timeline

• Start date: 2011-03-01
• Primary completion: 2014-03-01
• Completion: 2014-03-01
• First posted: 2014-04-09
• Last updated: 2014-04-09

Locations

1 site across 1 country: Germany