NCT02106624

A Trial to Assess the Effect of High Nitrogen Intake in Critically Ill Patients

The Efficacy and Safety of High Nitrogen Intake in Critically Ill Patients: a Randomized and Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 89 (actual)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The patients with sepsis are in high risk of malnutrition, which could contribute to infection, difficulty in weaning from ventilators. The investigators speculate whether nutrition therapy with high nitrogen could attenuate the malnutrition status and improve the outcome in these sepsis patients. In this prospective Randomized Controlled Trial, the investigators aim to compare high nitrogen intake with conventional nitrogen supply which were recommended in guidelines.

Conditions

• Critically Ill

Interventions

Type	Name	Description
OTHER	nitrogen supply	Nitrogen supply could be administered through amino acid in parenteral nutrition, proteins in enteral nutrition.

Timeline

• Start date: 2015-03-01
• Primary completion: 2020-01-01
• Completion: 2020-05-01
• First posted: 2014-04-08
• Last updated: 2020-05-27

Locations

1 site across 1 country: China