NCT02106533

Aerobic Exercise on Ventilatory Efficiency in CAD Patients

Effect of Aerobic Exercise Training on Ventilatory Efficiency in Patients With Coronary Artery Disease

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 123 (actual)
• Sponsor: Hospital TotalCor · Academic / Other
• Sex: All
• Age: 48 Years – 77 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the present study was to test the hypothesis that patients with coronary artery disease with lower aerobic fitness exhibit greater responsiveness on improving ventilatory efficiency after aerobic exercise training.

Detailed description

Measurements of ventilatory efficiency during cardiorespiratory exercise testing typically expressed as the minute ventilation/ carbon dioxide production ratio have been validated to be useful in assessing the presence and severity of both heart and lung diseases. In this context, previous studies have showed ventilatory inefficiency in patients with coronary artery disease suggests abnormalities in the distribution of ventilation and perfusion in the lungs. In addition, a growing body of studies has demonstrated that lower ventilatory efficiency during exercise is considered an important predictor of risk mortality, hospitalization, and other outcomes than peak VO2.

Conditions

• Coronary Artery Disease
• Exercise Addiction
• Complication, Cardio-respiratory

Interventions

Type	Name	Description
OTHER	Aerobic exercise training	The exercise training program was comprised of three 60-minute exercise sessions per week over a 3-month period. Each exercise session consisted of a 5 minute warm up, 30-50 minutes of aerobic exercise performed on a treadmill and 5 minutes of cool-down exercises. Aerobic exercise intensity was set at the corresponding heart rate between the VAT and RCP. All patients were able to achieve the set aerobic training intensity.

Timeline

• Start date: 2011-08-01
• Primary completion: 2012-06-01
• Completion: 2013-05-01
• First posted: 2014-04-08
• Last updated: 2014-04-08