NCT02102815

Efficacy of Preoperative Intravenous Dexamethasone in Primary Total Knee Arthroplasty

Efficacy of Preoperative Intravenous Dexamethasone in Controlling Postoperative Pain After Primary Total Knee Arthroplasty: A Randomized Double-blinded Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Thammasat University · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

To determine efficacy of preoperative IV dexamethasone for postoperative pain control after TKA.

Detailed description

Preoperative intravenous over 0.1 mg/kg of dexamethasone could be reduced pain after primary TKA.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Dexamethasone	Dexamethasone 0.15mg/kg mixed with NSS up to 50 mL IV slowly push over 5 minutes
DRUG	Normal saline	NSS 50 mL IV slowly push over 5 minutes

Timeline

• Start date: 2014-05-01
• Primary completion: 2016-02-01
• Completion: 2016-06-01
• First posted: 2014-04-03
• Last updated: 2019-01-15

Locations

1 site across 1 country: Thailand