NCT02095925

Cohort Study to Identify Cancer Patients at High Risk of Venous Thromboembolism

Microparticle's Procoagulant Activity to Identify Patients With Cancer and a High Risk for Venous Thrombosis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 900 (actual)
• Sponsor: Harry R. Buller · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cancer patients are at increased risk of deep venous thrombosis and pulmonary embolism, collectively termed venous thromboembolism (VTE). Risk assessment scores for VTE in cancer patients have been previously developed by the groups of Khorana and Vienna CATS. However, routine thromboprophylaxis for ambulatory cancer patients based on these scores is currently not recommended. In the investigators prospective, observational cohort study, the investigators aim to identify cancer patients at high risk for VTE based on clinical characteristics, coagulation biomarkers and the coagulant activity of tissue factor bearing microparticles.

Conditions

• Cancer
• Deep Venous Thrombosis
• Pulmonary Embolism

Timeline

• Start date: 2008-07-01
• Primary completion: 2016-06-01
• Completion: 2017-01-01
• First posted: 2014-03-26
• Last updated: 2017-01-18

Locations

7 sites across 4 countries: France, Italy, Mexico, Netherlands