NCT02095899

Effect of Rufinamide on Chronic Postthoracotomy Pain Syndrome

Effect of Rufinamide on Chronic Postthoracotomy Pain Syndrome. A Prospective, Randomized, Double-blind, Placebo Controlled, Monocenter Study.

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test if rufinamide has an effect on chronic neuropathic pain in patients with a post thoracotomy pain syndrome.

Detailed description

Patients with chronic neuropathic pain after thoracic surgery will be evaluated and treated with oxycodone. Patients with a stable analgesic regimen, not reaching a good pain relief will be randomized to receive Rufinamide (Inovelon)vs. Placebo as an ad-on treatment to oxycodone. Neurophysiological and clinical data will be monitored.

Conditions

• Peripheral Nerve Injuries
• Pain

Interventions

Type	Name	Description
DRUG	Rufinamide	2x200mg up to max 2x800mg a day Titration over 20days

Timeline

• Start date: 2014-03-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2014-03-26
• Last updated: 2015-07-21

Locations

1 site across 1 country: Switzerland