NCT02085759

T-helper 2 (Th2) Cytokine Responses in Overweight/Obese Subjects

Th2 Cytokine Responses in Overweight/Obese Subjects

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 46 (actual)
• Sponsor: West Penn Allegheny Health System · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Cytokines are chemicals that are naturally made by your body. Certain cytokine levels are changed in the blood of patients who develop allergies and/or asthma. Cytokine levels may also be changed in some individuals who are overweight or obese. The purpose of this study is to determine if certain cytokine levels differ based on a person's weight and whether or not they have allergies or asthma. Information gathered in this study will be compared to information gathered from subjects who have participated in another similar study for patients who have allergies and/or asthma.

Detailed description

The aims of this study are to: 1. Characterize the relationship between BMI and Th2 skewing in non-atopic adult subjects. 2. Compare these results to those previously obtained from atopic adult subjects It is expected that the results of this study will demonstrate enhanced Th2 skewing in overweight and obese atopic subjects as compared to non-atopic subjects. It is further anticipated that the results of this study will be used as preliminary data to generate an NIH grant application exploring the link between obesity and atopy.

Conditions

• Overweight
• Obesity

Timeline

• Start date: 2009-05-01
• Primary completion: 2010-12-01
• First posted: 2014-03-13
• Last updated: 2014-03-13

Locations

1 site across 1 country: United States