NCT02084381

PERCI- Medium Cut Off (MCO)

Permeability Enhancement to Reduce Chronic Inflammation _ Medium Cut Off (MCO) (Study no 1502)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Vantive Health LLC · Industry
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The medium cut-off dialysis membrane has been developed to provide a significantly extended molecular cut-off compared to conventional high-flux membranes. The medium cut-off membrane allows for a high permeability of molecules up to a molecular weight of 45 kDa and has a still limited permeability for albumin (68 kDa). The main goal of this project is the evaluation of the new, highly porous and selective dialysis membrane (MCO-Ci 400) for the treatment of patients with end-stage renal disease in hemodialysis mode and to study its potential to improve chronic inflammation.

Conditions

• Chronic Kidney Failure
• Chronic Inflammation

Interventions

Type	Name	Description
DEVICE	MCO-Ci 400	hemodialysis
DEVICE	Revaclear 400	hemodialysis

Timeline

• Start date: 2014-02-01
• Primary completion: 2014-07-01
• Completion: 2015-02-01
• First posted: 2014-03-12
• Last updated: 2025-03-13

Locations

2 sites across 1 country: Germany