Trials / Terminated
TerminatedNCT02083003
Polyamine-low Diet to Prevent Postoperative Pain After Cholecystectomy
- Status
- Terminated
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 38 (actual)
- Sponsor
- Hopital Foch · Academic / Other
- Sex
- All
- Age
- 18 Years – 76 Years
- Healthy volunteers
- Not accepted
Summary
It has been shown that N-methyl-D-aspartate (NMDA) receptor antagonists (such as ketamine) potentiate analgesic drug's efficacy. Polyamines are allosteric modulators of NMDA receptors. In animal studies, polyamine-free diet has shown antinociceptive properties. This research aims at evaluating analgesic properties of polyamine-low diet after laparoscopic cholecystectomy performed in an ambulatory setting.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Polyamine low-diet | |
| DIETARY_SUPPLEMENT | Liberal alimentation |
Timeline
- Start date
- 2013-01-01
- Primary completion
- 2015-01-01
- Completion
- 2015-01-01
- First posted
- 2014-03-11
- Last updated
- 2016-11-03
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02083003. Inclusion in this directory is not an endorsement.