Trials / Completed
CompletedNCT02081898
Effects of Long Term Calorie Restriction on Sphingomyelin and Amino Acids
Three-year Mild Calorie Restriction Partially Protects Against Age-related Increase in Sphingomyelin and Reduces Obesity-associated Amino Acids
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 120 (actual)
- Sponsor
- Yonsei University · Academic / Other
- Sex
- All
- Age
- 40 Years – 59 Years
- Healthy volunteers
- Not accepted
Summary
The effect of weight loss with long-term low calorie diet (LCD) on plasma metabolites is unknown. The aim was to examine whether a LCD-induced weight reduction results in changes in the extended plasma metabolites.
Detailed description
Overweight/obese subjects (25≤ BMI \<33 kg/m2) aged 40 to 59 years consumed a LCD (an approximate 100 kcal/day calorie deficit) or a weight-maintenance diet (control) in a randomized, controlled design with 3-year intervention period.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | LCD | approximate 100 kcal/d caloric deficit |
Timeline
- Start date
- 2010-06-01
- Primary completion
- 2010-08-01
- Completion
- 2010-08-01
- First posted
- 2014-03-07
- Last updated
- 2014-03-07
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT02081898. Inclusion in this directory is not an endorsement.