NCT02080962

Hypofractionated Radiotherapy for Nonmelanoma Skin Cancer

Hypofractionated Radiotherapy for Nonmelanoma Skin Cancer: Study Phase II Clinical Trial

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Barretos Cancer Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Radiotherapy is a treatment considered standard for non melanoma skin cancer. This institution uses schemes of 4 to 6 weeks of treatment. The objective of the study is to perform radiation therapy in 1 to 2 weeks, depending on the size of the lesion.

Detailed description

Delineation of radiation field * Gross tumor volume (GTV): disease clinically visible / palpable * clinical target volume (CTV): equal to GTV * planned treatment volume (PTV): * tumors ≤ 2 cm in diameter, with 5-10 mm CTV margin * tumors\> 2-5 cm in diameter, with 15-20 mm CTV margin * Marking the GTV and PTV pen back projection * photograph of the treatment area * protections of the normal structures with blocks of lead, if necessary Technical * Distance focus-skin Tube: 35 cm Locator: 30 and 40 cm * Sizes Tube: 2, 3 and 4 cm in diameter Finder: 6x8 cm, 8x10 cm * Energy: 80 kV 140 kv * Filter 80 kV, 2 mm Al 140 kv, 0.5 mm Copper * Current Draw: 20 mA Dose * tumors ≤ 2 cm in diameter: 5 fractions of 600 cGy, once a day, five times a week - TDF: 89 * tumors \> 2-5 cm in diameter: 10 fractions of 400 cGy, once a day, five times a week - TDF: 96 Clinical revisions every 5 weekly sessions, or a weekly and at the end of treatment.

Conditions

• Non-melanoma Skin Cancer

Interventions

Type	Name	Description
RADIATION	30 Gy in 5 fractions	5 fractions of 600 cGy, once a day, five times a week - TDF: 89
RADIATION	40 Gy in 10 fractions	tumors \> 2-5 cm in diameter: 10 fractions of 400 cGy, once a day, five times a week - TDF: 96

Timeline

• Start date: 2011-01-01
• Primary completion: 2014-02-01
• Completion: 2014-02-01
• First posted: 2014-03-07
• Last updated: 2014-03-07

Locations

1 site across 1 country: Brazil