NCT02079597

The Role of Ninjurin-1 During Systemic Inflammation

Prospective Study to Analyze Ninjurin-1 and Its Soluble Part During Systemic Inflammation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Dr. Patrick Meybohm, M.D. · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

* With the underlying study the investigators address the question if Ninjurin-1 (Ninj1) expression is altered in patients with systemic inflammatory response syndrome (SIRS) in comparison to healthy volunteers. * The adhesion molecule Ninj1 is induced following nerve injury where it contributes to nerve generation. Besides it is described to facilitate leukocyte migration especially in the nervous system. * The investigators hypothesize that Ninj1 expression is increased in SIRS patients, which will fortify its impact during inflammation and the transferability from bench to bedside.

Conditions

• Ninj1 Expression
• SIRS

Timeline

• Start date: 2014-02-01
• Primary completion: 2014-06-01
• Completion: 2014-09-01
• First posted: 2014-03-06
• Last updated: 2014-09-03

Locations

1 site across 1 country: Germany