Trials / Completed
CompletedNCT02078921
The Effects of Inorganic Nitrate on Cardiac Muscle in Angina
The Effects of Inorganic Nitrate on Cardiac Muscle: Physiology, Pharmacology and Therapeutic Potential in Patients Suffering From Angina
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- Sponsor
- University of Aberdeen · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Previous studies have shown that interventions which modestly increase blood nitrite\_ improve skeletal muscle function on exercise while sparing oxygen, and have been also shown to open up the blood flow during periods of oxygen deprivation. Inorganic nitrate in the diet is absorbed into the bloodstream, concentrated and reduced by bacteria in the mouth to nitrite, which is then absorbed into the bloodstream. . The purpose of this study is to look at the effects of oral inorganic nitrate supplementation on clinical markers of heart ischaemia and the frequency of angina.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sodium Nitrate | |
| DRUG | Placebo |
Timeline
- Start date
- 2012-10-01
- Primary completion
- 2014-12-01
- Completion
- 2014-12-01
- First posted
- 2014-03-05
- Last updated
- 2015-11-05
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT02078921. Inclusion in this directory is not an endorsement.