Clinical Trials Directory

Trials / Terminated

TerminatedNCT02078089

Oxcarbazepine Plus Morphine in Patients With Refractory Cancer Pain

A Phase Ib Study of Oxcarbazepine Plus Morphine in Patients With Refractory Cancer Pain

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
1 (actual)
Sponsor
Costantine Albany · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open-label, single arm, Phase Ib dose escalation study of Oxcarbazepine with morphine in patients with refractory cancer pain. The primary endpoint is to evaluate the safety and toxicity of the combination of Oxcarbazepine plus morphine. The secondary endpoints are improving pain control, reduce morphine use and improve the quality of life.

Conditions

Interventions

TypeNameDescription
DRUGMorphineMorphine will be given to patients as part of their standard care
DRUGOxcarbazepineCan be taken with or without food at the same time as morphine. Morphine will be provided to patients free of charge.

Timeline

Start date
2014-03-06
Primary completion
2014-12-11
Completion
2014-12-11
First posted
2014-03-05
Last updated
2017-01-31

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT02078089. Inclusion in this directory is not an endorsement.