Trials / Unknown
UnknownNCT02076685
NAT2 Genotyping in Re-challenge Protocol of INH Titration in Patients With Anti-TB Medications-induced Hepatitis
The Application of the N-acetyltransferase 2 (NAT2) Genotyping in Re-challenge Protocol of Isoniazid (INH) Titration in Patients With Anti-TB Medications-induced Hepatitis
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- National Taiwan University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To improve the treatment outcome in patients with tuberculosis and integrate the pharmacogenetics into clinical practice, the information of NAT2 genotyping was used in re-challenge protocol for isoniazid (INH) titration in patients with anti-tuberculosis medication-induced hepatitis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | isoniazid | dose adjustment according to the pharmacogenomic results |
Timeline
- Start date
- 2007-11-01
- Primary completion
- 2015-11-01
- Completion
- 2015-11-01
- First posted
- 2014-03-03
- Last updated
- 2014-03-17
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT02076685. Inclusion in this directory is not an endorsement.