Clinical Trials Directory

Trials / Completed

CompletedNCT02075541

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.

An Observer-blind Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
145 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
40 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this Phase II study is to assess the safety, reactogenicity and immunogenicity of the investigational Non-typeable Haemophilus influenzae (NTHi) vaccine in patients with moderate and severe persistent airflow obstruction.

Conditions

Interventions

TypeNameDescription
BIOLOGICALNTHi-10-AS01EIntramuscular vaccination in the deltoid region of the non-dominant arm according to protocol schedule.
DRUGNaCl PlaceboIntramuscular vaccination in the deltoid region of the non-dominant arm according to protocol schedule.

Timeline

Start date
2014-07-08
Primary completion
2017-04-19
Completion
2017-04-19
First posted
2014-03-03
Last updated
2018-08-01
Results posted
2018-08-01

Locations

14 sites across 2 countries: Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT02075541. Inclusion in this directory is not an endorsement.