NCT02070653

The Efficacy of Ticagrelor on Abdominal Aortic Aneurysm (AAA) Expansion

Does Ticagrelor Inhibit Growth of Small Abdominal Aortic Aneurysms? A Randomised Controlled Trial (TicAAA)

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 145 (actual)
• Sponsor: Uppsala University · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Abdominal aortic aneurysm (AAA) is a major health problem and ruptured AAA is a common cause of death in Europe and North America. A key limitation of contemporary treatment strategies of AAA is the lack of therapy directed at reducing expansion. Although surgical repair is an effective treatment for large AAA, it is associated with significant mortality and morbidity as well as substantial cost. The rationale for this randomized controlled study is to investigate whether treatment with Ticagrelor inhibits growth of small abdominal aortic aneurysms.

Conditions

• Abdominal Aortic Aneurysm

Interventions

Type	Name	Description
DRUG	Ticagrelor
DRUG	Placebo

Timeline

• Start date: 2014-03-01
• Primary completion: 2016-07-01
• Completion: 2017-07-01
• First posted: 2014-02-25
• Last updated: 2018-05-02

Locations

1 site across 1 country: Sweden