Trials / Unknown
UnknownNCT02069132
Validation of International Warfarin Pharmacogenetics Consortium (IWPC) Algorithm in Elderly Patients With Comorbidity
Prospective Validation of IWPC Pharmacogenetic Algorithm for Estimating the Appropriate Initial Dose of Warfarin in Elderly People (65 or Older) With Heart Valves Prostheses or Non Valvular Atrial Fibrillation and Comorbidity
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 376 (estimated)
- Sponsor
- University of Campania Luigi Vanvitelli · Academic / Other
- Sex
- All
- Age
- 65 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to validate the International Warfarin Pharmacogenetics Consortium (IWPC) algorithm in a prospective cohort of elderly people (65 years or older) with heart valves and/or nonvalvular atrial fibrillation (AF) and at least one comorbid condition, and to assess the algorithm's prognostic relevance.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Warfarin | warfarin treatment will be determined by treating physicians according to in-hospital guidelines, blindly to genotype assessment. |
Timeline
- Start date
- 2013-03-01
- Primary completion
- 2017-12-01
- Completion
- 2018-06-01
- First posted
- 2014-02-21
- Last updated
- 2017-04-27
Locations
3 sites across 1 country: Italy
Source: ClinicalTrials.gov record NCT02069132. Inclusion in this directory is not an endorsement.