NCT02067442

Prospective, Randomized, Double Blind Study Comparing IV vs PO Acetaminophen in Patients Undergoing Lumbar Discectomy

Prospective, Randomized, Double-blind, Placebo-Controlled Study to Compare the Effects of Intravenous Versus Oral Acetaminophen on Postoperative Clinical Outcomes After Ambulatory Lumbar Discectomy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Thomas Jefferson University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Both intravenous and oral acetaminophen have been shown to reduce post-operative pain scores when given preoperatively. This study investigates if there is a difference between the intravenous and the oral forms when given preoperatively to patients undergoing lumbar microdiscectomy. We hypothesize that the intravenous formulation does not improve pain scores or decrease opioid consumption during the first postoperative day compared to the oral formulation.

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	oral acetaminophen	1000 milligrams given orally before surgery
DRUG	intravenous acetaminophen	1000 milligrams of intravenous acetaminophen given before surgery

Timeline

• Start date: 2013-08-01
• Primary completion: 2015-07-01
• First posted: 2014-02-20
• Last updated: 2015-03-18

Locations

1 site across 1 country: United States