NCT02065141

Method To Measure Protein Digestion & Absorption

Validation Of A New Method To Simultaneously Measure Protein Digestion And Absorption

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Texas A&M University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is to validate a new method in healthy volunteers and those diagnosed with COPD and CHF that is able to measure protein digestion and absorption simultaneously. This method is used to quantify digestion and absorption in patients who are suspect of impaired digestion and absorption resulting in loss of nutrients.Findings may be used to develop treatment strategies to improve protein digestion and absorption in these patient groups.

Detailed description

The study involves 1 screening visit of approximately 1-2 hours and 1 test day of approximately 8 hours. On the study day protein digestion and absorption will be measured using a mixture of amino acids that are made slightly heavier than normal, called stable isotopes. Subjects will receive feeding by sips to monitor changes in digestion and absorption, which can be picked up by stable isotope technology.

Conditions

• Chronic Heart Failure
• Pulmonary Disorder, Chronic Obstructive

Interventions

Type	Name	Description
OTHER	sip feeding with stable isotope infusion	such as glycerol, D2O, tyrosine, phenylalanine, glucose, arginine, and citrulline

Timeline

• Start date: 2014-11-01
• Primary completion: 2019-01-19
• Completion: 2019-01-19
• First posted: 2014-02-17
• Last updated: 2022-02-07

Locations

1 site across 1 country: United States