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Trials / Completed

CompletedNCT02064569

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients

An Open Label Dose Escalation Clinical Trial to Evaluate the Safety and the Tolerability of GS010 (rAAV2/2-ND4) in Patients With Leber Hereditary Optic Neuropathy Due to Mutations in the Mitochondrial NADH Dehydrogenase 4 Gene

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
19 (actual)
Sponsor
GenSight Biologics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety and tolerability profile of ascending doses of GS010 in Leber Hereditary Optic Neuropathy (LHON) patients.

Conditions

Interventions

TypeNameDescription
GENETICGS010

Timeline

Start date
2014-02-13
Primary completion
2020-06-25
Completion
2020-06-25
First posted
2014-02-17
Last updated
2026-03-02

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT02064569. Inclusion in this directory is not an endorsement.

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients (NCT02064569) · Clinical Trials Directory