NCT02063919

Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 45 (actual)
• Sponsor: Shandong University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether an association between endomicroscopic pattern and colorectal mucosal microbiome exists.

Detailed description

The gut microbiome plays a pivotal role in the intestinal pathophysiology. The mucosal microbiome is in the front face of microbiome-host cross-talk. Confocal laser endomicroscopy (CLE) can provide realtime mucosal images during ongoing endoscopy. We hypothesized that the mucosal pattern, here evaluated by endomicroscopy, may constitute specific microbiome niches and participate the evolvement of the mucosal microbiome.

Conditions

• Colorectal Neoplasia
• Colorectal Inflammation
• Hyperplasia
• Mucosal Microbiome

Interventions

Type	Name	Description
OTHER	the mucosal microbiome in the biopsy specimen was analysed

Timeline

• Start date: 2013-11-01
• Primary completion: 2014-04-01
• Completion: 2014-06-01
• First posted: 2014-02-17
• Last updated: 2015-06-30

Locations

1 site across 1 country: China