NCT02063867

Active Bathing to Eliminate Infection (ABATE Infection) Trial

Cluster-Randomized Controlled Trial of Hospitals to Reduce Healthcare-Associated Infections and Readmissions Through Routine Bathing With Antiseptic Soap and Targeted Use of Nasal Antibiotic Ointment (ABATE Infection Trial)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 53 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: 12 Years
• Healthy volunteers: Not accepted

Summary

The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality improvement strategies to reduce multi-drug resistant organisms and healthcare-associated infections in non-critical care units. The two strategies to be evaluated are: * Arm 1: Routine Care Routine policy for showering/bathing * Arm 2: Decolonization Use of chlorhexidine as routine soap for showering or bed bathing for all patients Mupirocin x 5 days if MRSA+ by history, culture, or screen Note that enrolled "subjects" represents 53 individual HCA Hospitals (representing \~190 non-critical care units) that have been randomized.

Conditions

• Healthcare Associated Infections
• Methicillin Resistant Staphylococcus Aureus
• Multi Drug Resistant Organisms

Interventions

Type	Name	Description
DRUG	Arm 2: Decolonization	Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients. Topical intranasal mupirocin ointment (bilateral nares, twice daily) x5 days if non-critical care patients are MRSA+ by history, culture, or screen.

Timeline

• Start date: 2014-04-01
• Primary completion: 2019-02-01
• Completion: 2019-02-01
• First posted: 2014-02-14
• Last updated: 2019-07-12
• Results posted: 2019-07-12

Locations

52 sites across 1 country: United States