NCT02062710

Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

Antitussive Effect of a Naturally Flavored, Multi-Component Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Montefiore Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa flavoring, and, dextromethorphan syrup, compared with placebo.

Conditions

• Cough Reflex Sensitivity

Interventions

Type	Name	Description
DRUG	diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo	diphenhydramine 25 mg and phenylephrine 10 mg; dextromethorphan 30 mg; placebo.
DRUG	diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphan	diphenhydramine 25 mg and phenylephrine 10 mg; placebo; dextromethorphan 30 mg.
DRUG	dextromethorphan; diphenhydramine/phenylephrine/cocoa; placebo	dextromethorphan 30 mg; diphenhydramine 25 mg and phenylephrine 10 mg; placebo
DRUG	dextromethorophan; placebo; diphenhydramine/phenylephrine/cocoa	dextromethorphan 30 mg; placebo; diphenhydramine 25 mg and phenylephrine 10 mg
DRUG	placebo; diphenhydramine/phenylephrine/cocoa; dextromethorphan	placebo; diphenhydramine 25 mg and phenylephrine 10 mg; dextromethorphan 30 mg
DRUG	placebo; dextromethorphan; diphenhydramine/phenylephrine/cocoa	placebo; dextromethorphan 30 mg; diphenhydramine 25 mg and phenylephrine 10 mg

Timeline

• Start date: 2014-01-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2014-02-14
• Last updated: 2018-02-28
• Results posted: 2015-04-28

Locations

1 site across 1 country: United States