NCT02059369

Ablation of Complex Fractionated Electrograms With or Without Additional Linear Lesions for Persistent Atrial Fibrillation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Deutsches Herzzentrum Muenchen · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

While there is a consensus to perform pulmonary vein isolation (PVI) as a cornerstone for paroxysmal and persistent atrial fibrillation (AF), different additional ablation approaches are used for substrate modification: linear lesions, ablation of complex fractionated atrial electrograms (CFAE) or a combination of both. The aim of this study is to determine whether there is a difference in terms of freedom from arrhythmia recurrence between PVI with CFAE ablation in combination or not with linear lesions in patients with persistent AF.

Conditions

• Atrial Fibrillation
• Recurrence

Interventions

Type	Name	Description
PROCEDURE	PVI+CFAE+DCC	pulmonary vein Isolation (PVI), CFAE for substrate modification and direct current cardioversion (DCC) if AF persists
PROCEDURE	PVI, CFAE, anterior and roof line, DCC	PVI, CFAE ablation. If AF persists linear lesions (anterior and roof line), cardioversion if AF persists

Timeline

• Start date: 2012-08-01
• Primary completion: 2014-07-01
• Completion: 2014-12-01
• First posted: 2014-02-11
• Last updated: 2017-04-11

Locations

1 site across 1 country: Germany