Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT02058667

Reirradiation With Concurrent Paclitaxel for Breast Cancer

A Phase I Study of Twice Weekly Paclitaxel and Radical Re-irradiation Using Helical Tomotherapy for Aggressive Chest Wall Recurrences of Breast Cancer

Status
Withdrawn
Phase
Phase 1
Study type
Interventional
Enrollment
0 (actual)
Sponsor
University of Kentucky · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this trial in addition to a dose finding study for concurrent Paclitaxel, will be to establish a treatment algorithm for chest wall reirradiation. A nominal margin of at least 5cm will be used on the protocol and extending it to 7cm. Considering the standard treatment of breast cancer incorporates a cumulative dose of 60Gy, delivering an additional 50.4 Gy followed by a boost should target a total dose of 120 Gy.

Conditions

Interventions

TypeNameDescription
RADIATIONPaclitaxel+Initial Radiation+BoostPaclitaxel twice weekly + Initial Fields Radiation + Boost Radiation (10Gy)

Timeline

Start date
2014-07-01
Primary completion
2015-12-01
First posted
2014-02-10
Last updated
2016-11-15

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02058667. Inclusion in this directory is not an endorsement.