NCT02056340

Statin Therapy in Acute Influenza

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 116 (actual)
• Sponsor: Beth Israel Deaconess Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Influenza (the 'flu') is a common virus infecting approximately 5-20% of the population in the United States and causing as many as 500,000 deaths worldwide each year. Currently, there are only a few treatments for influenza infection and none of these target inflammation that can be caused by the virus. This study will test whether the anti-inflammatory effects of statins, a class of drugs most often used to treat high cholesterol, will decrease the severity of illness in patients who are infected with influenza by testing markers of inflammation in the blood and recording resolution of influenza illness.

Conditions

• Influenza

Interventions

Type	Name	Description
DRUG	Atorvastatin
DRUG	Placebo

Timeline

• Start date: 2013-10-01
• Primary completion: 2018-06-30
• Completion: 2018-06-30
• First posted: 2014-02-06
• Last updated: 2019-07-26
• Results posted: 2019-07-26

Locations

1 site across 1 country: United States