NCT02056028

Bile Leak After Liver Surgery

Validation of Our Policy of Long-term Drains Maintenance After Hepatic Resection: Results of a Prospective Cohort Analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 475 (actual)
• Sponsor: University of Milan · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The definition of biliary fistula is heterogeneous and the more accepted is that proposed by the ISGLS. We devised a precise definition of post-resectional biliary fistula and a well-established policy both for its disclosure and management.Aim was the validation of our definition, and management of biliary fistula after hepatic resection in a large prospective cohort of patients and its comparison with that of the International Study Group of Liver Surgery (ISGLS).

Detailed description

Data on abdominal drains and on clinical, pathological and short-term outcome were reviewed in a prospective cohort of patients who underwent hepatic resection between 2004 and 2012. Drains were maintained at least 7 days, and the bilirubin levels were measured in POD3, 5, and 7. Drains were removed if the bilirubin level in POD7 was inferior than in POD5, and less than 10 mg/dl. Statistical analysis on prognostic factors for biliary fistula was performed.

Conditions

• Bile Leak
• Hepatic Resection
• Liver Resection
• Hepatectomy
• Biliary Fistula

Interventions

Type	Name	Description
PROCEDURE	Hepatic resection

Timeline

• Start date: 2004-01-01
• Primary completion: 2012-12-01
• Completion: 2014-02-01
• First posted: 2014-02-05
• Last updated: 2014-02-05

Locations

1 site across 1 country: Italy