NCT02054936

Evaluation of Wound Drainage After Knee or Hip Arthroplasty

Evaluation of Wound Drainage Following Rivaroxaban (Xarelto) or Warfarin (Coumadin) for Post op Venous Thromboembolism (VTE) Prophylaxis, After Knee or Hip Arthroplasty a Randomized Study.

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To compare side effects and complications relating to use of warfarin or rivaroxaban, tolerance and/or toxicity of these two agents such as drop in hemoglobin post operatively, extent of bruising, quantity of wound drainage, duration of drainage, wound swelling, sub and supra-therapeutic prothrombin times, need for transfusion, and patient tolerance in two randomized groups. Return visits to the operating room, length of stay, and VTE rates will also be compared.

Conditions

• Complications; Arthroplasty

Interventions

Type	Name	Description
DRUG	Rivaroxaban (Xarelto)	To date there has been little attention to evaluating differences in wound complications following TJA among patients treated with rivaroxaban compared to warfarin.
DRUG	Warfarin (Coumadin)	To date there has been little attention to evaluating differences in wound complications following TJA among patients treated with rivaroxaban compared to warfarin.

Timeline

• Start date: 2014-03-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2014-02-04
• Last updated: 2015-12-07

Locations

1 site across 1 country: United States