Trials / Withdrawn
WithdrawnNCT02051075
Fertilizations With Immotile Sperm: Pentoxyphylline Activation Alone, or With Chemical Oocyte Activation
A Randomized Controlled Trial to Compare Fertilizations With Immotile Sperm After Pentoxyphylline Activation Alone, or With Chemical Oocyte Activation
- Status
- Withdrawn
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Rambam Health Care Campus · Academic / Other
- Sex
- All
- Age
- 20 Years – 35 Years
- Healthy volunteers
- Not accepted
Summary
Immotile sperm is a rather frequent problem encountered in IVF patients. Treatment is usually based on inducing motility with pentoxyphylline (PXN) followed by ICSI. However, fertilization rate with this method is still lower compared with ICSI using motile sperm. One of the reasons for that is the immotile sperm inability to activate the oocyte Our research hypothesis is that better fertilization rate can be accomplished in these cases by combining PXN sperm activation with Ca ionophore oocyte activation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | PXN sperm treatment | immotile sperm activation with PXN |
| BIOLOGICAL | Sperm activation with PXN and oocyte activation |
Timeline
- Start date
- 2014-03-01
- Primary completion
- 2015-05-01
- Completion
- 2015-05-01
- First posted
- 2014-01-31
- Last updated
- 2015-05-06
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT02051075. Inclusion in this directory is not an endorsement.