NCT02050425

Breath Analysis in Obstructive Sleep Apnoea

Exhaled Breath Analysis by Mass Spectrometry in Patients With Obstructive Sleep Apnoea - a Randomised Placebo-controlled Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Clinical trial in patients with obstructive sleep apnoea that are randomised to either continue or withdraw continuous positive airway pressure therapy to identify a disease-specific exhaled breath pattern by mass spectrometry.

Detailed description

Randomised placebo-controlled trial (therapeutic vs. subtherapeutic continuous positive airway pressure \[CPAP\]) including 30 OSA patients to define the effects of CPAP withdrawal (subtherapeutic CPAP) on the composition of exhaled breath analysed by mass spectrometry for identification of OSA specific markers.

Conditions

• Obstructive Sleep Apnoea (OSA)

Interventions

Type	Name	Description
DEVICE	Placebo-CPAP device	short-term CPAP withdrawal by the use of Placebo-CPAP
DEVICE	CPAP	Patients continue therapeutic CPAP therapy

Timeline

• Start date: 2014-01-01
• Primary completion: 2014-10-01
• Completion: 2014-10-01
• First posted: 2014-01-30
• Last updated: 2014-11-25

Locations

1 site across 1 country: Switzerland