NCT02048891

Ovulation Trigger With hCG Compared to GnRH Agonist in Patients With Repeated IVF Failures

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Rambam Health Care Campus · Academic / Other
• Sex: Female
• Age: 35 Years – 44 Years
• Healthy volunteers: Not accepted

Summary

Ovulation trigger is needed in in vitro fertilization (IVF) to get mature eggs. Routinely, human chorionic gonadotropin (hCG) is used for that purpose given its similarity to the natural hormone that does this job in a natural cycle (luteinizing hormone, LH). In a natural cycle another hormone takes part in the process (follicle stimulating hormone, FSH). To induce a natural-like ovulation surge that includes LH and FSH , gonadotropin releasing hormone (GnRH) agonist can be given. The purpose of this study is to find out which approach may work better in IVF patients who experienced 4 IVF failures.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	GnRH agonist trigger
DRUG	hCG trigger

Timeline

• Start date: 2014-10-01
• Primary completion: 2015-01-01
• Completion: 2015-04-01
• First posted: 2014-01-29
• Last updated: 2015-06-08
• Results posted: 2015-06-08

Locations

1 site across 1 country: Israel