NCT02047617

Study of Safety and Efficacy on Neuromyopathy of Early Standing With the Assistance of Tilt Table in Critically Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 145 (actual)
• Sponsor: Centre Chirurgical Marie Lannelongue · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Critically ill patients frequently develop muscle weakness due to critical illness-related acute neuropathy and/or myopathy. This disorder is associated with difficulties in weaning from mechanical ventilation, prolonged intensive care unit and hospital stay, and increased mortality rates. In addition, many patients continue to suffer from decreased exercise capacity and quality of life for months to years after the acute event. Besides controlling risk factors, no specific prevention or treatment exists. Recommendations advice to start early with active and passive exercise in critically ill patients (1). Having critically ill patients alert and engaged in progressive rehabilitation leading to mobilization, despite the use of life support therapies may reduce muscle atrophy and lead to improved strength and physical function (2). This randomized controlled trial was designed to investigate whether a daily training session using a tilt table, started early in stable critically ill patients with an expected prolonged ICU stay, could induce a beneficial effect on exercise performance, quadriceps force and functional autonomy at ICU and hospital discharge compared to a standard physiotherapy program.

Conditions

• Patients Are Recruited From One Thoracic and Cardiac Surgery ICU

Interventions

Type	Name	Description
DEVICE	the standard physiotherapy group	Mobilization and rehabilitation program is progressively introduced after clinical stabilization
DEVICE	standing table group	The protocol involved a stepwise process to gradually raise the subject into a standing position on the standing table platform

Timeline

• Start date: 2013-08-01
• Primary completion: 2015-08-01
• Completion: 2015-10-01
• First posted: 2014-01-28
• Last updated: 2017-02-27

Locations

1 site across 1 country: France