NCT02041871

Interest of PReOPerative Immunonutrition in Liver Surgery for Cancer

Interest of Preoperative Immunonutrition in Liver Resection for Cancer

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 399 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To study the efficacy of preoperative immunonutrition in reducing postoperative morbidity after liver resection for cancer.

Detailed description

Perioperative immunonutrition has been developed to improve the immuno metabolic host response and outcome in postoperative period and has been proven to be beneficial in reducing significantly postoperative infectious complications and length of hospital stay in patients undergoing elective gastrointestinal surgery for tumors. To date, the effects of preoperative oral immunonutrition (ORAL IMPACT) in non cirrhotic patients undergoing liver resection for cancer are unknown. The purpose of this study is to determine whether the administration of a short-term preoperative oral immunonutrition can reduce postoperative morbidity in non-cirrhotic patients undergoing liver resection for malignant tumours.

Conditions

• Hepatectomy
• Elective Hepatectomy
• Malignant Tumors

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral immunonutrition	Powder 74g within 250ml of water, 3 times per day during 7 days before surgery
DIETARY_SUPPLEMENT	Placebo	Powder 74g within 250ml of water, 3 times per day during 7 days before surgery

Timeline

• Start date: 2013-09-01
• Primary completion: 2018-09-13
• Completion: 2018-09-13
• First posted: 2014-01-22
• Last updated: 2018-10-11

Locations

1 site across 1 country: France