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UnknownNCT02041260

A Phase II Trial of Cabozantinib for the Treatment of Radioiodine (RAI)-Refractory Differentiated Thyroid Carcinoma (DTC) in the First-line Setting

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
43 (actual)
Sponsor
Thomas Jefferson University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Phase II, non-randomized, open-label study to determine the efficacy of cabozantinib as a firstline treatment for patients with differentiated thyroid cancer (DTC). Subjects will receive drug at a starting dose of 60mg PO QD. Subjects can receive drug as long as they continue to derive clinical benefit or until they experience unacceptable drug-related toxicity.

Conditions

Interventions

TypeNameDescription
DRUGCabozantinib

Timeline

Start date
2014-01-01
Primary completion
2022-05-01
Completion
2022-05-01
First posted
2014-01-22
Last updated
2021-10-15

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02041260. Inclusion in this directory is not an endorsement.

A Phase II Trial of Cabozantinib for the Treatment of Radioiodine (RAI)-Refractory Differentiated Thyroid Carcinoma (DTC (NCT02041260) · Clinical Trials Directory