Trials / Terminated
TerminatedNCT02037412
Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome
- Status
- Terminated
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 148 (actual)
- Sponsor
- Yonsei University · Academic / Other
- Sex
- All
- Age
- 20 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The investigators hypothesized that ticagrelor may enhance endothelial healing after DES implantation by increasing adenosine concentrations by the inhibition of adenosine uptake into erythrocytes, compared to clopidogrel. Thus, the investigators will evaluate the extent of endothelialization (stent strut coverage) and neointimal hyperplasia (neointimal thickness) 3 months after DES implantation by optical coherence tomography (OCT)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ticagrelor | Ticagrelor - 180 mg loading and 90 mg bid maintenance for 3 months |
| DRUG | Clopidogrel | Clopidogrel - 600 mg loading and 75 mg qd maintenance for 3 months |
Timeline
- Start date
- 2014-01-01
- Primary completion
- 2016-09-30
- Completion
- 2016-09-30
- First posted
- 2014-01-15
- Last updated
- 2019-03-29
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT02037412. Inclusion in this directory is not an endorsement.