NCT02033577

Effects of Long Biliopancreatic Limb Versus Long Alimentary Limb in Superobesity, a Randomized Study

Effects of Long Biliopancreatic Limb vs Long Alimentary Limb in Superobesity

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Aleris Obesity · Industry
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Surgical bypassing of a longer section of the small bowel (when doing a gastric bypass operation) gives better results on body weight in the superobese. We do not yet know whether it is beneficial to exclude more of the proximal small bowel or more of the distal. Side effects of bypassing can also be different. Study aims at clarifying possible differences in effects and side-effects of these two surgical-technical variations.

Detailed description

Randomisation in the OR between long biliopancreatic limb and long alimentary limb. GAstric component identical. Perioperative biopsies to assess mucosal properties at the gastrojejunostomy and the enteroanastomosis. Repeat biopsies (gastroscopy) at one year to identify changes in the mucosa at the Gastroenteroanastomosis.

Conditions

• Severe Obesity

Interventions

Type	Name	Description
PROCEDURE	Distal gastrojejunal bypass	RYGB with 200 cm BP limb and 150 cm common limb, effect on EWL, QoL and complications
PROCEDURE	RYGB	RYGB with 60 cm BP limb and 150 cm alimentary limb, effect on

Timeline

• Start date: 2011-08-01
• Primary completion: 2016-08-01
• Completion: 2016-08-01
• First posted: 2014-01-13
• Last updated: 2015-03-17

Locations

1 site across 1 country: Sweden