NCT02032394

Effect of Chlorhexidine on Bacteriuria

Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 105 (estimated)
• Sponsor: Mashhad University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study is conducted to determine and compare the effect of applying Povidone-iodine and Chlorhexidine solutions for perinea washing on bacteriuria rate and type in patients with urinary catheter in intensive care unit.

Detailed description

This is a double blind randomized study with control group. The population is patients in intensive care unit of Shahid Beheshti hospital of Babol city. Main include criteria are 18-55 years old, need to having urine catheter for 10 days at least and no urinary infection in catheterization time. Main exclude criteria are appearing genital wound, allergic or dermatitis disorders. Sample size include 105 patients dividing in three equal groups of Povidone-iodine, Chlorhexidine and Normal saline randomly. Interventions are Washing perinea area and catheter first 5 centimeters by 15 ml of Povidone-iodine 10%, Chlorhexidine .2% or Normal saline .9%, 3 times a day for 10 days. Urine analysis are performed in days 1,3,5,7 and 9 after catheterization and urine cultures are performed in days 5 and 10 after catheterization for detection of bacteriuria and microorganism type.

Conditions

• Urinary Tract Infection
• Nosocomial Infection
• Bacteriuria

Interventions

Type	Name	Description
DRUG	Povidone-iodine	15 ml 10%, 3 imes a day for 10 days /external use for Washing perinea area and catheter first 5 centimeters
DRUG	Chlorhexidine	15 ml .2%, 3 imes a day for 10 days /external use for Washing perinea area and catheter first 5 centimeters
DRUG	Normal saline	15 ml .9%, 3 imes a day for 10 days /external use for Washing perinea area and catheter first 5 centimeters

Timeline

• Start date: 2013-07-01
• Primary completion: 2014-02-01
• Completion: 2014-04-01
• First posted: 2014-01-10
• Last updated: 2014-01-10

Locations

1 site across 1 country: Iran