Trials / Terminated
TerminatedNCT02031588
Impact of Ceftriaxone and/or Fluoroquinolone (FQ) Treatment on the Gut Microbiota of Hospitalized Patients.
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 77 (actual)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Observational study of the effects of antibiotics on commensal flora. Realization of stool samples and nasal swabs before and after antibiotic therapy.
Detailed description
The emergence of resistance to fluoroquinolone (FQ) and is a major problem worldwide. The commensal flora is the main reservoir for antibiotic resistance. Understanding the factors (environmental, patient-related, dosis-related, drug-related…) involved in the emergence of resistance to fluoroquinolones in the commensal flora of patients treated with a FQ, may help prevent it and preserve the efficiency of these important antibiotics. Samples of digestive flora will be collected from hospitalized patients before receiving a FQ or Ceftriaxone, at the end of the treatment and 3 month after the end of treatment. Clinical data will be collected.
Conditions
Timeline
- Start date
- 2012-12-01
- Primary completion
- 2014-09-01
- Completion
- 2015-09-01
- First posted
- 2014-01-09
- Last updated
- 2015-12-09
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02031588. Inclusion in this directory is not an endorsement.