NCT02031497

Comparison of the Effects of a 12-Week Consumption of Two Carbonated Beverages on Insulin Sensitivity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Institute For European Expertise in Physiology · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether consumption of carbonated drinks containing sweeteners affect insulin sensitivity.

Detailed description

Sweeteners are natural or synthetic sugar substitutes which provide a sweetness taste to drink and food with few or no additional calories. Sweeteners are widely used in commercialized beverages. Despite some debate, no significant toxicity was demonstrated at a reasonable level of consumption (less than 20 cans per day). However little data is available on the metabolic effects of a regular consumption of beverages containing sweeteners. The objective of the study is to evaluate the effect of a regular consumption (twice a day for 12 weeks) of a carbonated drink with sweeteners, in a normal diet, compared with unsweetened sparkling water on insulin sensitivity in healthy normoweight and overweight subjects.

Conditions

• Glucose Homeostasis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Drink with sweeteners	Subjects will have to consume a 330ml can of a drink with sweeteners twice per day as part of their usual fluid intake for 12 weeks.
DIETARY_SUPPLEMENT	Drink without sweeteners	Subjects will have to consume a 330ml can of a drink without sweeteners twice per day as part of their usual fluid intake for 12 weeks.

Timeline

• Start date: 2012-10-01
• Primary completion: 2014-04-01
• Completion: 2014-12-01
• First posted: 2014-01-09
• Last updated: 2017-03-03

Locations

1 site across 1 country: France