NCT02031237

MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 52 (actual)
• Sponsor: University of Michigan Rogel Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to assess changes in vascular permeability in the brain tumor, and in the surrounding brain, due to radiation therapy, using Magnetic Resonance Imaging (MRI).

Conditions

• Brain Metastases

Interventions

Type	Name	Description
RADIATION	Single Fraction Stereotactic Radiosurgery (SRS)	Intervention will not be assigned by the investigator. Treatment determination will be made prior to study enrollment.
RADIATION	Fractionated Whole Brain Radiation Therapy (WBRT)	Intervention will not be assigned by the investigator. Treatment determination will be made prior to study enrollment.
RADIATION	Fractionated Stereotactic Radiation Therapy (FSRT)	Intervention will not be assigned by the investigator. Treatment determination will be made prior to study enrollment.
DEVICE	Magnetic Resonance Imaging (MRI) Assessments	MRI scans will include a routine clinical MRI series.

Timeline

• Start date: 2005-04-01
• Primary completion: 2014-05-01
• Completion: 2014-12-01
• First posted: 2014-01-09
• Last updated: 2019-07-26
• Results posted: 2019-07-26

Locations

1 site across 1 country: United States