Trials / Withdrawn
WithdrawnNCT02029261
Observational Study of Insulin Resistance and Muscle Wasting After Burn Injury
Project 4: Molecular Mechanisms in Burn-induced Insulin Resistance in Humans
- Status
- Withdrawn
- Phase
- —
- Study type
- Observational
- Enrollment
- 0 (actual)
- Sponsor
- Massachusetts General Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to examine important and significant problems, that of insulin resistance and muscle wasting after burn injury.
Detailed description
Burn injury induces insulin resistance and our investigators have previous shown the importance of insulin receptor substrate 1 (IRS-1)-mediated pathways. This project will establish the inhibitory effects of burn injury on IRS-1 mediated signaling in human skeletal muscle of burn patients.
Conditions
Timeline
- Start date
- 2014-05-01
- Primary completion
- 2018-05-01
- Completion
- 2018-05-01
- First posted
- 2014-01-07
- Last updated
- 2019-03-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02029261. Inclusion in this directory is not an endorsement.