Clinical Trials Directory

Trials / Unknown

UnknownNCT02027090

High Dose Versus Routine Dose Icotinib in Advanced Non-small Cell Lung Cancer Patients With Stable Disease

High Dose Versus Routine Dose Icotinib in Pretreated Non-small Cell Lung Cancer Patients With Stable Disease: a Phase II Randomized Study

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
64 (estimated)
Sponsor
Betta Pharmaceuticals Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

We hypothesize that higher dose icotinib is related with better efficacy. The primary objective is to compare the progression-free survival of higher dose and routine dose of icotinib in treating pretreated advanced non-small cell lung cancer patients with stable disease after 8-week routine dose icotinib treatment.

Conditions

Interventions

TypeNameDescription
DRUGRoutine dose icotinibIcotinib is administered 125 mg three times daily.
DRUGHigher dose icotinibAfter 8-week induction of icotinib with a dose of 125 mg three times daily, icotinib is administered 375 mg three times per day.

Timeline

Start date
2014-01-01
Primary completion
2016-06-01
Completion
2016-12-01
First posted
2014-01-03
Last updated
2015-05-22

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT02027090. Inclusion in this directory is not an endorsement.