NCT02026739

The Optimal Intraoperative Supplemental Oxygen Administration During Minimally Invasive Esophagectomy

The Impact of Different Intraoperative Supplemental Oxygen Administration on the Pulmonary Function Following Minimally Invasive Esophagectomy: A Prospective Randomized Controlled Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Tan, Lijie · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The study hypothesized that a relative low oxygen concentration (40%) supplemental would be advantageous to protect the pulmonary function of patients, comparied with conventional high oxygen concentration (80%). Therefore we raise this prospective randomized controlled research.

Detailed description

Patients underwent minimally invasive esophagectomy in Zhongshan Hospital of Fudan University will be enrolled and be randomizedly assigned to low oxygen concentration (40%) supplemental or high oxygen concentration(80%) supplemental group. Intra-operative and post-operative pressure of Oxygen in Arterial Blood will be examined, and the surgical outcome will be recorded in the two groups.

Conditions

• Oxygenation Index

Interventions

Type	Name	Description
PROCEDURE	low supplemental oxygen concentration	low supplemental oxygen concentration would be used during the surgery
PROCEDURE	high supplemental oxygen concentration (conventional)	high supplemental oxygen concentration would be used during the surgery

Timeline

• Start date: 2013-09-01
• Primary completion: 2014-06-01
• Completion: 2014-07-01
• First posted: 2014-01-03
• Last updated: 2014-01-03

Locations

1 site across 1 country: China