NCT02022579

DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer

A Multi-Center Study Evaluating the Utility of Diffusion Weighted Imaging for Detection and Diagnosis of Breast Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: American College of Radiology Imaging Network · Network
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A type of magnetic resonance imaging called diffusion weighted imaging (DWI) will be tested to define cancerous from non-cancerous lesions in the breast.

Detailed description

For this study, the investigators plan to evaluate DWI scans performed in women with breast lesions identified by conventional breast MRI. The investigators will determine whether an ADC threshold can be defined for distinguishing benign and malignant lesions on DWI, assess the difference in ADC cutoffs for mass and non-mass lesions, and investigate the potential improvement in accuracy using techniques such as nonzero minimum b-value (to remove perfusion effects in the ADC measures) and normalized ADC measures (to account for variations in water content and other factors).

Conditions

• Breast Cancer
• BIRADS 3
• BIRADS 4
• BIRADS 5

Interventions

Type	Name	Description
PROCEDURE	DCE-MRI and DWI	DCE-MRI defined lesion(s) compared with biopsy results or 1-year follow up

Timeline

• Start date: 2014-01-01
• Primary completion: 2018-11-01
• Completion: 2019-03-01
• First posted: 2013-12-30
• Last updated: 2018-10-11

Locations

1 site across 1 country: United States